4 July 2021 - Late treatment study
The use of vitamin C in the intensive care unit during the COVID-19 pandemic
et al., The European Research Journal, doi:10.18621/eurj.938778 (Peer Reviewed)
Retrospective 160 ICU patients, 32 with raised neutrophil/lymphocyte ratio treated with vitamin C, showing no significant differences.
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risk of death, 9.3% lower, RR 0.91, p = 0.69, treatment 17 of 32 (53.1%), control 75 of 128 (58.6%), NNT 18.
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risk of mechanical ventilation, 1.1% higher, RR 1.01, p = 1.00, treatment 23 of 32 (71.9%), control 91 of 128 (71.1%).
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. |
This study is excluded in the after exclusion results of meta
analysis:
substantial unadjusted confounding by indication likely.
Özgünay et al., 7/4/2021, retrospective, Turkey, Europe, peer-reviewed, 7 authors.
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