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0 0.5 1 1.5 2+ Mortality 44% Improvement Relative Risk ICU admission 10% c19vitaminc.com Simsek et al. Vitamin C for COVID-19 LATE TREATMENT Favors vitamin C Favors control
Simsek, 139 patient vitamin C late treatment study: 44% lower mortality [p=0.19] and 10% lower ICU admission [p=0.66] https://c19p.org/simsekc
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Effects of high dose vitamin C administration in Covid-19 patients
Simsek et al., Annals of Medical Research, doi:10.5455/annalsmedres.2020.10.1043
27 Sep 2021    Source   PDF   Share   Tweet
Retrospective 139 hospitalized patients in Turkey, 58 treated with high dose vitamin C, showing improved kidney functioning with treatment. Mortality was lower with treatment, but not reaching statistical significance with the small sample size.
risk of death, 44.1% lower, RR 0.56, p = 0.18, treatment 6 of 58 (10.3%), control 15 of 81 (18.5%), NNT 12.
risk of ICU admission, 10.2% lower, RR 0.90, p = 0.66, treatment 18 of 58 (31.0%), control 28 of 81 (34.6%), NNT 28.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Simsek et al., 9/27/2021, retrospective, Turkey, Europe, peer-reviewed, 16 authors.
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Late treatment
is less effective
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