27 September 2021 - Late treatment study
Effects of high dose vitamin C administration in Covid-19 patients
et al., Annals of Medical Research, doi:10.5455/annalsmedres.2020.10.1043 (Peer Reviewed)
Retrospective 139 hospitalized patients in Turkey, 58 treated with high dose vitamin C, showing improved kidney functioning with treatment. Mortality was lower with treatment, but not reaching statistical significance with the small sample size.
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risk of death, 44.1% lower, RR 0.56, p = 0.18, treatment 6 of 58 (10.3%), control 15 of 81 (18.5%), NNT 12.
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risk of ICU admission, 10.2% lower, RR 0.90, p = 0.66, treatment 18 of 58 (31.0%), control 28 of 81 (34.6%), NNT 28.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. |
Simsek et al., 9/27/2021, retrospective, Turkey, Europe, peer-reviewed, 16 authors.
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