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0 0.5 1 1.5 2+ Mortality 21% Improvement Relative Risk ICU admission -2% c19vitaminc.com Suna et al. Vitamin C for COVID-19 LATE TREATMENT Favors vitamin C Favors control
Suna, 323 patient vitamin C late treatment study: 21% lower mortality [p=0.52] and 2% higher ICU admission [p=1] https://c19p.org/suna
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Effect of high-dose intravenous vitamin C on prognosis in patients with SARS-CoV-2 pneumonia
Suna et al., Med. Clin. (Barc.), doi:10.1016/j.medcli.2021.04.010
11 May 2021    Source   PDF   Share   Tweet
Retrospective 323 hospitalized patients, 153 treated with vitamin C, showing no significant differences. Patients in each group were in different time periods, with the vitamin C group first. Time based confounding is possible due to improvements in SOC.
risk of death, 21.3% lower, RR 0.79, p = 0.52, treatment 17 of 153 (11.1%), control 24 of 170 (14.1%), NNT 33.
risk of ICU admission, 1.9% higher, RR 1.02, p = 1.00, treatment 11 of 153 (7.2%), control 12 of 170 (7.1%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: substantial confounding by time likely due to declining usage over the early stages of the pandemic when overall treatment protocols improved dramatically.
Suna et al., 5/11/2021, retrospective, Turkey, Europe, peer-reviewed, 5 authors.
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