Retrospective 8,634 hospitalized patients in India, showing lower mortality with high-dose vitamin C in unadjusted results. No group details are provided, the text and table appear to show different results, and some numbers do not match.
Vishnuram et al., 6/30/2021, retrospective, India, South Asia, peer-reviewed, 5 authors.
risk of death, 54.2% lower, RR 0.46, p = 0.03, treatment 164 of 8634 (1.9%), control 10 of 241 (4.1%).
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details, minimal details of groups provided.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.