Xing et al., Journal of Pharmaceutical and Biomedical Analysis,
doi:10.1016/j.jpba.2021.113927 (Peer Reviewed)
Vitamin C supplementation is necessary for patients with coronavirus disease: An ultra-high-performance liquid chromatography-tandem mass spectrometry finding
Prospective study with 31 COVID-19 patients and 60 controls reporting on a new method to assess plasma vitamin C concentrations. Vitamin C was deficient (11.4µmol/l vs. 52µmol/l for healthy controls), and returned to a normal range (76µmol/l) with intravenous vitamin C. Authors recommend high dose intravenous vitamin C for COVID-19 patients at a dose of 100mg/kg/day.
Xing et al., 1/27/2021, peer-reviewed, 13 authors.